Quantitation of Trace Levels of DNA Released from Disrupted Adeno-Associated Virus Gene Therapy Vectors
Jared S. Bee, Kristin O'Berry, Yu Zhang, Megan Kuhn Phillippi, Akanksha Kaushal, Roberto A. DePaz, Tristan Marshall
Topics & Concepts
Adeno-associated virusDNACapsidGenetic enhancementChemistryMolecular biologyVectors in gene therapyExogenous DNADegradation (telecommunications)GeneBiophysicsChromatographyBiologyRecombinant DNABiochemistryViral vectorVector (molecular biology)TelecommunicationsComputer scienceVirus-based gene therapy researchRNA Interference and Gene DeliveryCRISPR and Genetic Engineering