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Incorporating HIV Screening With COVID-19 Testing in an Urban Emergency Department During the Pandemic

Kimberly A. Stanford, Moira McNulty, Jessica Schmitt, Dylan Eller, Jessica P. Ridgway, Kathleen V. Beavis, David Pitrak

2021JAMA Internal Medicine31 citationsDOIOpen Access PDF

Abstract

The Table shows the distribution of observed vs predicted risk based on the COVID-GRAM score by quintile of predicted risk. The COVID-GRAM predictions were similar to the observed outcomes among patients in the first 4 quintiles of risk for critical illness, but it overestimated the predicted risk of events in the highest quintile by almost 2-fold. The accuracy of the COVID-GRAM in the cohort was moderate, with an AUC of 0.72 (95% CI, 0.64-0.80) compared with an AUC of 0.88 (95% CI, 0.84-0.93) in the Chinese validation cohort. 1 A score of 89 or higher showed a sensitivity of 97.7% and a specificity of 32.7% for development of critical illness.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)PandemicCohortCritical illnessSeverity of illnessCohort studyEmergency departmentInternal medicineRisk assessmentDiseaseEmergency medicineCritically illInfectious disease (medical specialty)PsychiatryComputer securityComputer scienceHIV/AIDS Research and InterventionsCOVID-19 Clinical Research StudiesPneumocystis jirovecii pneumonia detection and treatment