Site-specific polymerase incorporation of consecutive ligand-containing nucleotides for multiple metal-mediated base pairing
Takahiro Nakama, Yusuke Takezawa, Mitsuhiko Shionoya
Abstract
-responsive DNAzyme. Accordingly, this research will open new routes for the construction of metal-responsive DNA architectures that are manipulated by multiple metal-mediated base pairing.
Topics & Concepts
NucleotideBase pairLigand (biochemistry)ChemistryBase (topology)PolymeraseDNAStereochemistryDNA polymeraseEnzymeNucleobaseMetalCombinatorial chemistryBiochemistryReceptorOrganic chemistryGeneMathematicsMathematical analysisAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryNanocluster Synthesis and Applications