Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery
Lulu Xue, Gan Zhao, Ningqiang Gong, Xuexiang Han, Sarah J. Shepherd, Xinhong Xiong, Zebin Xiao, Rohan Palanki, Junchao Xu, Kelsey L. Swingle, Claude C. Warzecha, Rakan El‐Mayta, Vivek Chowdhary, Il‐Chul Yoon, Jingcheng Xu, Jiaxi Cui, Yi Shi, Mohamad‐Gabriel Alameh, Karin Wang, Lili Wang, Darrin J. Pochan, Drew Weissman, Andrew E. Vaughan, James M. Wilson, Michael J. Mitchell
Topics & Concepts
SiloxaneIntracellularNanoparticleNanotechnologyMessenger RNAChemistryCell biologyBiophysicsMaterials scienceBiochemistryPolymerBiologyOrganic chemistryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesNanopore and Nanochannel Transport Studies