Litcius/Paper detail

Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery

Lulu Xue, Gan Zhao, Ningqiang Gong, Xuexiang Han, Sarah J. Shepherd, Xinhong Xiong, Zebin Xiao, Rohan Palanki, Junchao Xu, Kelsey L. Swingle, Claude C. Warzecha, Rakan El‐Mayta, Vivek Chowdhary, Il‐Chul Yoon, Jingcheng Xu, Jiaxi Cui, Yi Shi, Mohamad‐Gabriel Alameh, Karin Wang, Lili Wang, Darrin J. Pochan, Drew Weissman, Andrew E. Vaughan, James M. Wilson, Michael J. Mitchell

2024Nature Nanotechnology89 citationsDOIOpen Access PDF

Topics & Concepts

SiloxaneIntracellularNanoparticleNanotechnologyMessenger RNAChemistryCell biologyBiophysicsMaterials scienceBiochemistryPolymerBiologyOrganic chemistryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesNanopore and Nanochannel Transport Studies