Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury
Tianpeng Chen, Yingying Wei, Gaoyang Zhu, Huajun Zhao, Xingxian Zhang
Topics & Concepts
ARDSChemistryPharmacologyIn vivoInflammationMAPK/ERK pathwayLungIn vitroMedicineBiochemistryImmunologySignal transductionInternal medicineBiologyBiotechnologySynthesis of heterocyclic compoundsPharmacological Receptor Mechanisms and EffectsImmune Response and Inflammation