Litcius/Paper detail

The High Rates of Comorbidity among Neurodevelopmental Disorders: Reconsidering the Clinical Utility of Distinct Diagnostic Categories

Eleni Bonti, Irini K. Zerva, Christiana Koundourou, Maria Sofologi

2024Journal of Personalized Medicine41 citationsDOIOpen Access PDF

Abstract

The boundaries between neurodevelopmental disorders are often indistinct, even among specialists. But do these boundaries exist, or do experts struggle to distinguish and categorize symptoms in order to arrive at a dominant diagnosis while comorbidity continually leaves questions about where each disorder ends and begins? What should be reconsidered? The introduction of the term 'spectrum of neurodevelopmental disorders' could pave the way for a re-appraisal of the clinical continuum of neurodevelopmental disorders. This study aims to highlight the problems that emerge in the field of the differential diagnosis of neurodevelopmental disorders and propose a renegotiation of the distinctiveness criteria.

Topics & Concepts

Optimal distinctiveness theoryComorbidityCategorizationNeurodevelopmental disorderPsychiatric comorbidityMedicinePerspective (graphical)PsychiatryPsychologyAutismComputer sciencePsychotherapistArtificial intelligenceAutism Spectrum Disorder ResearchWilliams Syndrome ResearchGenomics and Rare Diseases