The key role of protodeauration in the gold-catalyzed reaction of 1,3-diynes with pyrrole and indole to form complex heterocycles
Ioannis Stylianakis, Olalla Nieto Faza, Carlos Silva López, Antonios Kolocouris
Abstract
The mechanism of indole and carbazole formation <italic>via</italic> a formal [4 + 2] cycloaddition strategy is dominated by the protodeauration step.
Topics & Concepts
ChemistryIndole testPyrroleCycloadditionCarbazoleCatalysisCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalytic Alkyne ReactionsCyclization and Aryne ChemistrySynthetic Organic Chemistry Methods