Two antibacterial spiro compounds from the roots of <i>Artemisia pallens</i> wall: evidence from molecular docking
Varsha S. Honmore, Arun D. Natu, Vijay M. Khedkar, Manisha Arkile, Dhiman Sarkar, Supada R. Rojatkar
Abstract
. Molecular docking study could further help in understanding the various interactions between these compounds and DNA gyrase active site in detail and thereby could provide valuable insight into the mechanism of action.
Topics & Concepts
DNA gyraseChemistryAntibacterial activityStereochemistryBacillus subtilisDocking (animal)AcetoneMycobacterium tuberculosisBacteriaEscherichia coliBiologyBiochemistryGeneMedicineNursingTuberculosisPathologyGeneticsEssential Oils and Antimicrobial ActivityPhytochemistry and Biological ActivitiesPlant biochemistry and biosynthesis