Kartogenin-loaded hydrogel promotes intervertebral disc repair via protecting MSCs against reactive oxygen species microenvironment by Nrf2/TXNIP/NLRP3 axis
Feng Wang, Kai Guo, Liping Nan, Shuguang Wang, Jiawei Lu, Qiang Wang, Zhaoyu Ba, Yu‐Feng Huang, Desheng Wu
Topics & Concepts
Mesenchymal stem cellReactive oxygen speciesStem cellPLGAChemistryCell biologyExtracellular matrixIntervertebral discBiomedical engineeringMedicineAnatomyIn vitroBiologyBiochemistrySpine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationPlant Toxicity and Pharmacological Properties