Ag(I)-Catalyzed Addition of Cyclopropenones and Nitrones to Access Imides
Jinglei Xu, Hu Tian, Jiahao Kang, Wu-Xiang Kang, Wei Sun, Rui Sun, Ya‐Min Li, Meng Sun
Abstract
An unprecedented Ag-catalyzed addition reaction of cyclopropenones and nitrones to access imides was developed. Sequential C-C bond cleavage, N-O bond cleavage, and Mumm rearrangement were uncovered in this process. This protocol exhibited high efficiency, regioselectivity, good yields, and a broad tolerance of various functional groups.
Topics & Concepts
ChemistryRegioselectivityCatalysisCleavage (geology)Bond cleavageFunctional groupCombinatorial chemistryMedicinal chemistryOrganic chemistryGeotechnical engineeringEngineeringPolymerFracture (geology)Cyclopropane Reaction MechanismsCatalytic Alkyne ReactionsCatalytic C–H Functionalization Methods