Synthesis and anticancer potential of novel 5,6-oxygenated and/or halogenated steroidal d-homo lactones
Ivana Kuzminac, Dimitar Jakimov, Sofija S. Bekić, Anđelka S. Ćelić, Maja Marinović, Marina P. Savić, Vidak Raičević, Vesna Kojić, Marija N. Sakač
Topics & Concepts
ChemistryCytotoxicityADMECell cultureA549 cellSteroidLipinski's rule of fiveApoptosisStereochemistryBiochemistryIn silicoIn vitroGeneticsBiologyHormoneGeneEstrogen and related hormone effectsSteroid Chemistry and BiochemistryComputational Drug Discovery Methods