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Epidemiology and the Impact of Therapies on the Outcome of COVID-19 in Patients With Inflammatory Bowel Disease

Alfredo Papa, Antonio Gasbarrini, Antonio Tursi

2020The American Journal of Gastroenterology31 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: It has been hypothesized that people suffering from inflammatory bowel disease (IBD) have an increased risk of coronavirus disease (COVID-19). However, it is not known whether immunosuppressive therapies exacerbate the COVID-19 outcome. METHODS: We reviewed data on the prevalence and clinical outcomes of COVID-19 in patients with IBD. RESULTS: COVID-19 prevalence in patients with IBD was comparable with that in the general population. Therapies using antitumor necrosis factor-α agents have been associated with better clinical outcomes. DISCUSSION: Management and treatments provided by gastroenterologists were effective in reducing COVID-19 risk. Antitumor necrosis factor-α agents seem to mitigate the course of COVID-19.

Topics & Concepts

MedicineInflammatory bowel diseaseCoronavirus disease 2019 (COVID-19)EpidemiologyDiseaseInternal medicineInflammatory Bowel DiseasesUlcerative colitisPopulationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Crohn's diseaseRisk factorIntensive care medicineImmunologyInfectious disease (medical specialty)Environmental healthInflammatory Bowel DiseaseCOVID-19 Clinical Research StudiesImmune responses and vaccinations
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