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On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum

Daniel W. Bradbury, Jasmine T. Trinh, Milo J. Ryan, Cassandra M. Cantu, Jiakun Lu, Frances D. Nicklen, Yushen Du, Ren Sun, Benjamin M. Wu, Daniel T. Kamei

2021The Analyst21 citationsDOIOpen Access PDF

Abstract

We developed an innovative 3D printed casing that incorporates a lateral-flow immunoassay, dehydrated signal enhancement reagents, and a sealed buffer chamber.

Topics & Concepts

SIGNAL (programming language)ChemistryReagentCasingImmunoassayChromatographySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)MedicineComputer sciencePathologyImmunologyPhysicsPhysical chemistryGeophysicsProgramming languageAntibodyDiseaseInfectious disease (medical specialty)Biosensors and Analytical DetectionSARS-CoV-2 detection and testingAdvanced Nanomaterials in Catalysis
On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum | Litcius