Heterogeneity, inherent and acquired drug resistance in patient-derived organoid models of primary liver cancer
Linfeng Xian, Pei Zhao, Xi Chen, Zhimin Wei, Hongxiang Ji, Jun Zhao, Wenbin Liu, Zishuai Li, Donghong Liu, Xue Han, You‐Wen Qian, Hui Dong, Xiong Zhou, Junyan Fan, Xiaoqiong Zhu, Jianhua Yin, Xiaojie Tan, Dongming Jiang, Hongping Yu, Guangwen Cao
Topics & Concepts
OrganoidSorafenibCancer researchHepatocellular carcinomaDownregulation and upregulationEpithelial–mesenchymal transitionLiver cancerDrug resistanceMedicineBiologyGeneCell biologyBiochemistryMicrobiologyCancer Cells and MetastasisLiver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis