Three-Dimensional Structures of Carbohydrates and Where to Find Them
Sofya I. Scherbinina, Filip V. Toukach
Abstract
Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed.
Topics & Concepts
GlycobiologyComputer scienceVisualizationInformaticsData scienceData miningBiologyEngineeringGlycanMolecular biologyElectrical engineeringGlycoproteinGlycosylation and Glycoproteins ResearchGenomics and Phylogenetic StudiesMicrobial Metabolites in Food Biotechnology