MiR-30a-5p promotes cholangiocarcinoma cell proliferation through targeting SOCS3
Jia Wei Zhang, Xing Wang, Gao Chao Li, Dong Wang, Sheng Han, Yao Dong Zhang, Chen Luo, Hongwei Wang, Wang Jiang, Chang Xian Li, Xiang Cheng Li
Abstract
Background: MicroRNAs (miRNAs) play important roles in the occurrence and development of cancers. In this project, we aimed to explore the role and molecular mechanism of mir-30a-5p in cholangiocarcinoma (CCA).
Topics & Concepts
microRNACell growthTransfectionApoptosisLuciferaseCancer researchSOCS3Downregulation and upregulationCellReporter geneChemistryBiologyMolecular biologyCell cultureSTAT3Gene expressionGeneBiochemistryGeneticsMicroRNA in disease regulationCircular RNAs in diseasesCancer-related molecular mechanisms research