Condensation of pyrylium salts with mixed anhydrides: aryl ethers, aryl amines and sterically congested aromatics
Daniel Grabowski, Susanne Alef, Steven Becker, Ute Müller, Gregor Schnakenburg, Sigurd Höger
Abstract
Condensation of 2,4,6-triaryl pyrylium salts with mixed anhydrides, formed in situ from α-functionalized sodium acetates and an anhydride solvent, leads in good yields to the corresponding 2,4,6-triaryl benzenes functionalized at their 1-position.
Topics & Concepts
ChemistryArylSteric effectsCondensationSolventOrganic chemistryPolymer chemistrySodiumThermodynamicsPhysicsAlkylCatalytic Cross-Coupling ReactionsFluorine in Organic ChemistrySynthesis and Characterization of Pyrroles