Dual-crosslinking gelatin-hyaluronic acid methacrylate based biomimetic PDAC desmoplastic niche enhances tumor-associated macrophages recruitment and M2-like polarization
Di Wu, Tiancheng Gong, Zhongxiang Sun, Xihao Yao, Dongzhi Wang, Q Chen, Qingsong Guo, Xiaohong Li, Yibing Guo, Yuhua Lu
Topics & Concepts
Tumor microenvironmentHyaluronic acidMacrophage polarizationExtracellular matrixDownregulation and upregulationTumor progressionCancer researchMacrophageSelf-healing hydrogelsCell biologyChemistryBiologyIn vitroBiochemistryTumor cellsGeneticsGeneOrganic chemistryImmune cells in cancerCancer Cells and MetastasisEpigenetics and DNA Methylation