Litcius/Paper detail

Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects

Shicheng Xu, An-ping Guo, Nannan Chen, Wei Dai, Huanaoyu Yang, Wenqin Xie, Mengjie Wang, Qidong You, Xiaoli Xu

2021European Journal of Medicinal Chemistry14 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryHsp90Heat shock proteinIn vivoLead compoundPharmacologyColitisAnti-inflammatoryBiochemistryIn vitroGeneImmunologyBiotechnologyBiologyMedicineHeat shock proteins researchthermodynamics and calorimetric analysesATP Synthase and ATPases Research