Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis
Adam Laycock, Nathaniel J. Clark, Robert Clough, Rachel Smith, Richard D. Handy
Abstract
size limit of detection, and proportions of recovery), making comparison between some studies more difficult. In order to establish standardised protocols for regulatory use, effort is needed to: develop certified reference materials, achieve international agree on nomenclature and the use of control samples, and to create a decision tree to help select the best sample preparation for the type of tissue matrix.
Topics & Concepts
Protocol (science)Sample preparationCertified reference materialsComputer scienceConsistency (knowledge bases)Sample (material)Matrix (chemical analysis)Biochemical engineeringBiological materialsNanotechnologyParticle (ecology)Risk analysis (engineering)Computational biologyChemistryMaterials scienceBiologyDetection limitChromatographyPathologyMedicineEngineeringEcologyAlternative medicineArtificial intelligenceNanoparticles: synthesis and applicationsAnalytical chemistry methods developmentHeavy metals in environment