Gut microbiome and resistome changes during the first wave of the COVID-19 pandemic in comparison with pre-pandemic travel-related changes
Ye Peng, Dengwei Zhang, Ting Chen, Yankai Xia, Peng Wu, Wai‐Kay Seto, Anita L. Kozyrskyj, Benjamin J. Cowling, Jincun Zhao, Hein M. Tun
Abstract
COVID-19-associated measures had a greater impact on gut microbiota, antibiotic resistance genes and biocide resistance genes than did pre-pandemic international travel. During the COVID-19 pandemic, Actinobacteria richness decreased, whereas genes conferring resistance to beta-lactam, polystyrene and phthalate increased. Such alterations may affect both colonization resistance and acquisition and spread of antimicrobial resistance in future travels.
Topics & Concepts
ResistomePandemicMicrobiomeMedicineAntibiotic resistanceMetagenomicsActinobacteriaCoronavirus disease 2019 (COVID-19)MicrobiologyAntibioticsBiologyGeneGeneticsInfectious disease (medical specialty)Pathology16S ribosomal RNADiseaseIntegronGut microbiota and healthTravel-related health issuesHIV/AIDS Research and Interventions