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Cross-Dehydrogenative Coupling of Strong C(sp<sup>3</sup>)–H with <i>N</i>-Heteroarenes through Visible-Light-Induced Energy Transfer

Haitao Tian, Hui Yang, Chao Tian, Guanghui An, Guangming Li

2020Organic Letters99 citationsDOI

Abstract

The sustainable cross-dehydrogenative coupling of strong C(sp3)–H with N-heteroarenes has been developed using an efficient organic photocatalyst. It features atomic- and step-economy, and acid-free conditions. Mechanism studies suggest a previous elusive energy transfer pathway from photocatalyst to N-heteroarenes and oxidants.

Topics & Concepts

ChemistryCoupling (piping)Energy transferPhotocatalysisPhotochemistryVisible spectrumEnergy (signal processing)Chemical physicsCatalysisOptoelectronicsOrganic chemistryPhysicsMaterials scienceQuantum mechanicsMetallurgyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
Cross-Dehydrogenative Coupling of Strong C(sp<sup>3</sup>)–H with <i>N</i>-Heteroarenes through Visible-Light-Induced Energy Transfer | Litcius