Targeted AURKA degradation: Towards new therapeutic agents for neuroblastoma
Muhammad Rishfi, Simon Krols, Fien Martens, Sarah-Lee Bekaert, Ellen Sanders, Aline Eggermont, Fanny De Vloed, Joshua Robert Goulding, Martijn Risseeuw, Jan J. Molenaar, Bram De Wilde, Serge Van Calenbergh, Kaat Durinck
Topics & Concepts
NeuroblastomaChemistryLinkerCancer researchKinaseProtein kinase domainTargeted therapyCell cultureBiochemistryBiologyCancerInternal medicineMedicineMutantGeneComputer scienceOperating systemGeneticsProtein Degradation and InhibitorsNeuroblastoma Research and TreatmentsUbiquitin and proteasome pathways