Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix
Yan Cheng, Janusz Franco‐Barraza, Yuan Wang, Chaonan Zheng, Li Zhang, Yanghui Qu, Ya‐Qiu Long, Edna Cukierman, Zeng-jie Yang
Topics & Concepts
Stromal cellAstrocyteExtracellular matrixSonic hedgehogHedgehog signaling pathwayCell biologyMedulloblastomaBiologyCell cultureIn vitroCancer researchSignal transductionChemistryNeuroscienceCentral nervous systemBiochemistryGeneticsHedgehog Signaling Pathway StudiesGlioma Diagnosis and TreatmentEpigenetics and DNA Methylation