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Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity

Franziska Haase, Jana Pöhmerer, Mina Yazdi, Melina Grau, Yanira Zeyn, Ulrich Wilk, Tobias Burghardt, Miriam Höhn, Christoph Hieber, Matthias Bros, Ernst Wagner, Simone Berger

2023European Journal of Pharmaceutics and Biopharmaceutics19 citationsDOI

Topics & Concepts

SpleenChemistryTransfectionSelectivityDendritic cellMessenger RNACell biologyImmunologyBiochemistryGeneBiologyImmune systemCatalysisRNA Interference and Gene DeliveryImmune Cell Function and InteractionHIV Research and Treatment
Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity | Litcius