Arginine-Based Poly(I:C)-Loaded Nanocomplexes for the Polarization of Macrophages Toward M1-Antitumoral Effectors
Tamara G. Dacoba, Clément Anfray, Francesco Mainini, Paola Allavena, Marı́a José Alonso, Fernando Torres Andón, José Crecente‐Campo
Abstract
Overall, these enveloped poly(I:C) nanocomplexes might represent a therapeutic option to fight cancer through the induction of cytotoxic M1-polarized macrophages.
Topics & Concepts
Flow cytometryChemistryMacrophage polarizationViability assayBiophysicsChemokineIn vitroMolecular biologyMacrophageReceptorBiologyBiochemistryImmune cells in cancerNanoplatforms for cancer theranosticsCancer Research and Treatments