Porous protein crystals: synthesis and applications
Alec A Jones, Christopher D. Snow
Abstract
directed evolution and rational redesign based on the known crystal structures. LPCs possess extremely high solvent content, as well as extremely high surface area to volume ratios. Because of these characteristics, LPCs continue to be explored in diverse applications including catalysis, targeted therapeutic delivery, templating of nanostructures, structural biology. This Feature review article will describe several of the existing platforms in detail, with particular focus on LPC synthesis approaches and reported applications.
Topics & Concepts
Protein crystallizationPorosityMaterials scienceNanotechnologySolventPorous mediumChemical engineeringCrystallographyChemistryCrystallizationOrganic chemistryComposite materialEngineeringEnzyme Structure and FunctionProtein purification and stabilityBiochemical and Structural Characterization