Litcius/Paper detail

A synonymous mutation in IGF-1 impacts the transcription and translation process of gene expression

S. Y. Wang, Yunyun Cheng, S.C. Liu, Yanli Xu, Yan Gao, Chunlei Wang, Z.G. Wang, Tianqi Feng, Guanhong Lu, Jie Song, Peijun Xia, Linlin Hao

2021Molecular Therapy — Nucleic Acids25 citationsDOIOpen Access PDF

Abstract

expression and biological function through the transcription and translation processes.

Topics & Concepts

BiologyMutantSilent mutationGeneGeneticsSynonymous substitutionMutationTranslation (biology)Gene expressionEukaryotic translationTranscription (linguistics)Transcription factorTranslational efficiencyCodon usage biasMessenger RNAMissense mutationGenomePhilosophyLinguisticsRNA modifications and cancerRNA and protein synthesis mechanismsRNA Research and Splicing