Aseptic meningitis after BNT-162b2 COVID-19 vaccination
Amanda Chan, Benjamin Yong‐Qiang Tan, Yihui Goh, Shaun Sy Tan, Paul Anantharajah Tambyah
Abstract
The COVID-19 pandemic has had an unprecedented impact on healthcare systems globally, giving rise to significant morbidity and mortality. Vaccination has been widely regarded as the most important strategy to contain the pandemic. Whilst local side-effects of the BNT-162b2 (Pfizer-BioNTech) vaccine are well known, concern has emerged due to sporadic reports of immune-mediated adverse effects (Cines and Bussel, 2021; Rela et al., 2021). As of August 19, 2021, 4.54 million individuals had received COVID-19 vaccines in Singapore (Oxford Martin School UoO, 2021). We report a case series of two patients who developed aseptic meningitis after vaccination.
Topics & Concepts
Aseptic meningitisVaccinationPandemicCoronavirus disease 2019 (COVID-19)MedicineMeningitis2019-20 coronavirus outbreakPediatricsVirologyInternal medicineOutbreakDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchImmunodeficiency and Autoimmune DisordersPneumocystis jirovecii pneumonia detection and treatment