A tumor microenvironment-responsive Co/ZIF-8/ICG/Pt nanoplatform for chemodynamic and enhanced photodynamic antitumor therapy
Fan Jiang, Yajie Zhao, Chunzheng Yang, Ziyong Cheng, Min Liu, Bengang Xing, Binbin Ding, Ping’an Ma, Jun Lin
Abstract
to produce hydroxyl radicals (˙OH) for CDT. The multifunctional nanoplatform CZIP showed high biosafety and a good antitumor effect, which would provide a new route for cancer therapy.
Topics & Concepts
Photodynamic therapyIndocyanine greenTumor microenvironmentSinglet oxygenChemistryCancer researchHydrogen peroxidePhotosensitizerReactive oxygen speciesCancer cellTumor hypoxiaHypoxia (environmental)ApoptosisCancerPhotochemistryTumor cellsMedicineOxygenRadiation therapyBiochemistryPathologyInternal medicineOrganic chemistryNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisPhotodynamic Therapy Research Studies