Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway
Fangying Yan, Rongchen Liu, Xinyu Zhuang, Ruoshui Li, Haiming Shi, Xiufang Gao
Topics & Concepts
CardiotoxicityDoxorubicinSalidrosideGene knockdownSOD2PharmacologyReactive oxygen speciesCardiac dysfunctionDownregulation and upregulationSmall interfering RNAMedicineCancer researchBiologyOxidative stressChemotherapyApoptosisTransfectionHeart failureSuperoxide dismutaseInternal medicineCell biologyBiochemistryGeneChemotherapy-induced cardiotoxicity and mitigationMedicinal Plants and Bioactive CompoundsParaoxonase enzyme and polymorphisms