FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
Robin Schwarzer, Huipeng Jiao, Laurens Wachsmuth, Achim Tresch, Manolis Pasparakis
Topics & Concepts
NecroptosisFADDPyroptosisRIPK1BiologyCaspase 8Cell biologyProgrammed cell deathInflammasomeInflammationIleitisCaspaseApoptosisCancer researchImmunologyMedicineInternal medicineBiochemistryCrohn's diseaseDiseaseInflammasome and immune disordersCell death mechanisms and regulationinterferon and immune responses