Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
Colby R. Maldini, Daniel T. Claiborne, Ken Okawa, Tao Chen, Derrick L. Dopkin, Xiaochuan Shan, Karen A. Power, Radiana Trifonova, Katharine L. Krupp, Meredith Phelps, Vladimir Vrbanac, Serah Tanno, Timothy Bateson, George J. Leslie, James A. Hoxie, Christian L. Boutwell, James L. Riley, Todd M. Allen
Topics & Concepts
Chimeric antigen receptorCD28T cellViremiaImmunologyBiologyCytotoxic T cellHumanized mouseCD8Cancer researchImmune systemVirologyVirusIn vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology