A modular microfluidic platform for serial enrichment and harvest of pure extracellular vesicles
Hogyeong Gwak, Sunyoung Park, Haeun Yu, Kyung‐A Hyun, Hyo‐Il Jung
Abstract
). The two chips can be modularized or individually operated, depending on the clinical applications such as diagnostics and therapeutics. For the diagnostic applications, the EVs on microbeads can be directly subjected to the molecular analysis whereas the pure EVs should be released from the microbeads for the therapeutic treatments. This study reveals that the fabricated modular chip can be appropriately employed as a platform for EV-related research tools.
Topics & Concepts
Extracellular vesiclesMicrofluidicsModular designElutionChemistryChromatographyNanotechnologyVesicleThroughputComputer scienceMaterials scienceMembraneBiochemistryBiologyCell biologyOperating systemTelecommunicationsWirelessExtracellular vesicles in diseaseNanopore and Nanochannel Transport StudiesMicrofluidic and Bio-sensing Technologies