Design, synthesis, and anti-inflammatory activity of indole-2-formamide benzimidazole[2,1-<i>b</i>]thiazole derivatives
Hai-Feng Lin, Yucai Jiang, Zhi-Wei Chen, Linlin Zheng
Abstract
, while reducing GSH content, thereby facilitating the iron death process. Consequently, compound 13b showed promise for future development as an anti-inflammatory drug.
Topics & Concepts
BenzimidazoleThiazoleFormamideIndole testChemistryCombinatorial chemistryStereochemistryOrganic chemistrySynthesis and biological activityBioactive Compounds and Antitumor AgentsSynthesis and Characterization of Heterocyclic Compounds