Litcius/Paper detail

Salidroside derivative SHPL-49 attenuates glutamate excitotoxicity in acute ischemic stroke via promoting NR2A-CAMKⅡα-Akt /CREB pathway

Dong Xie, Pei Zhang, Suxin You, Yue SHEN, Wenwen Xu, Changsen Zhan, Jiange Zhang

2024Phytomedicine15 citationsDOI

Topics & Concepts

ExcitotoxicitySalidrosideCREBGlutamate receptorPharmacologyPI3K/AKT/mTOR pathwayCAMKChemistryProtein kinase BMedicineNMDA receptorInternal medicineApoptosisBiochemistryTranscription factorPhosphorylationProtein kinase AReceptorGeneAutophosphorylationMedicinal Plants and Bioactive CompoundsSaffron Plant Research StudiesNeurological Disorders and Treatments