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Household food insecurity is associated with diabetic ketoacidosis but not severe hypoglycemia or glycemic control in youth and young adults with <scp>youth‐onset</scp> type 2 diabetes

Lauren A. Reid, Jason A. Mendoza, Anwar T. Merchant, Marco Geraci, Beth A. Reboussin, Faisal Malik, Alice M. Ellyson, Dana Dabelea, Lina Merjaneh, Santica M. Marcovina, Eva Lustigova, Jean M. Lawrence, Angela D. Liese

2022Pediatric Diabetes25 citationsDOIOpen Access PDF

Abstract

OBJECTIVE: To examine the association between household food insecurity (HFI), glycemic control, severe hypoglycemia and diabetic ketoacidosis (DKA) among youth and young adults (YYA) with youth-onset type 2 diabetes. RESEARCH DESIGN AND METHODS: and analyzed as a continuous and categorical variable (optimal: <7.0%, suboptimal: ≥7.0%-9.0%, poor: >9.0%). Acute complications included self-reported severe hypoglycemia or DKA in the last 12 months. Adjusted logistic and linear regression were used for binary and continuous outcomes, respectively. RESULTS: >9.0% compared to 55% without HFI. Adjusted models showed no associations between HFI and glycemic control. Of those with HFI, 14.4% reported experiencing DKA and 4.7% reported severe hypoglycemia. YYA with HFI had 3.08 times (95% CI: 1.18-8.06) the odds of experiencing DKA as those without HFI. There was no association between HFI and severe hypoglycemia. CONCLUSIONS: HFI was associated with markedly increased odds of DKA but not with glycemic control or severe hypoglycemia. Future research among YYA with type 2 diabetes should evaluate longitudinally whether alleviating HFI reduces DKA.

Topics & Concepts

MedicineHypoglycemiaGlycemicDiabetic ketoacidosisType 1 diabetesOdds ratioDiabetes mellitusLogistic regressionYoung adultOddsType 2 diabetesKetoacidosisCross-sectional studyInternal medicinePediatricsDemographyEndocrinologySociologyPathologyFood Security and Health in Diverse PopulationsObesity, Physical Activity, DietDiabetes Management and Research