Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade
Stefan Roth, Jiayu Cao, Vikramjeet Singh, Steffen Tiedt, Gabriel Hundeshagen, Ting Li, Julia D. Boehme, Dhruv Chauhan, Jie Zhu, Alessio Ricci, Oliver Gorka, Yaw Asare, Jun Yang, Mary S. Lopez, Markus Rehberg, Dunja Bruder, Shengxiang Zhang, Olaf Groß, Martin Dichgans, Veit Hornung, Arthur Liesz
Topics & Concepts
AIM2PyroptosisInflammasomeBiologyProgrammed cell deathImmunologyMonocyteImmunosuppressionInflammationT cellApoptosisImmune systemBiochemistryInflammasome and immune disordersImmune Response and InflammationBiomarkers in Disease Mechanisms