Zinc-catalyzed asymmetric nitrooxylation of β-keto esters/amides with a benziodoxole-derived nitrooxy transfer reagent
Bin Li, Xuan Cheng, Zhen‐Yu Guan, Si‐Yuan Li, Tao Huo, Guo Cheng, Yan-Hui Fan, Fang-Shuai Zhou, Qing‐Hai Deng
Abstract
Zinc-catalyzed asymmetric nitrooxylation to afford a series of α-nitrooxy β-keto esters/amides in high yields and with low to moderate enantioselectivities has been disclosed.
Topics & Concepts
ChemistryZincReagentCatalysisOrganic chemistryMedicinal chemistryCombinatorial chemistryOxidative Organic Chemistry ReactionsSynthesis and Catalytic ReactionsAsymmetric Synthesis and Catalysis