Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection
Michela Carraro, Andrea Carrer, Andrea Urbani, Paolo Bernardi
Topics & Concepts
Mitochondrial permeability transition poreAdenine nucleotide translocatorMitochondrial matrixCardioprotectionBiophysicsMitochondrial membrane transport proteinInner mitochondrial membraneVoltage-dependent anion channelATP synthaseMitochondrionTransition (genetics)NucleotideCell biologyAdenine nucleotideBiologyChemistryPermeability (electromagnetism)DruggabilityBiochemistryBacterial outer membraneCytosolMembraneEnzymeProgrammed cell deathGeneIschemiaApoptosisCardiologyEscherichia coliMedicineFuel Cells and Related MaterialsMitochondrial Function and PathologyATP Synthase and ATPases Research