Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling
Amanda L. Miller, Lauren K. Nicastro, Shingo Bessho, Kaitlyn Grando, Aaron P. White, Yi Zhang, Gillian Queisser, Bettina A. Buttaro, Çağla Tükel
Abstract
Recent studies provided important insight into our understanding of the role of c-di-GMP signaling and the regulation of enteric biofilms. Despite an improved understanding of how c-di-GMP signaling regulates S. Typhimurium biofilms, the processes that affect the intracellular c-di-GMP levels and the formation of multicellular communities in vivo during infections remain unknown.
Topics & Concepts
BiofilmSalmonella entericaMicrobiologyBiologySalmonellaFlagellumMotilityCell biologyMulticellular organismBacteriaBiochemistryGeneGeneticsBacterial biofilms and quorum sensingVibrio bacteria research studiesAntibiotic Resistance in Bacteria