Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
Yu Zhou, Xiaoguang Li, Kerong Chen, Qian Ba, Xu Zhang, Jingquan Li, Jinfang Wang, Hui Wang, Hong Liu
Topics & Concepts
Ovarian cancerArtemisininIn vivoCytotoxicityChemistryPharmacologyPharmacophoreCancerTherapeutic indexCancer researchCancer cellIn vitroLiver cancerCytotoxic T cellCell growthApoptosisDrugBiochemistryImmunologyBiologyInternal medicineMedicinePlasmodium falciparumBiotechnologyMalariaComputational Drug Discovery MethodsMalaria Research and ControlSynthesis and bioactivity of alkaloids