Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma
Surabhi Talele, Wenjuan Zhang, Danielle M. Burgenske, Minjee Kim, Afroz S. Mohammad, Sonja Dragojevic, Shiv K. Gupta, Ranjit S. Bindra, Jann N. Sarkaria, William F. Elmquist
Topics & Concepts
TemozolomideBrain tumorCancer researchIn vivoChemotherapyMedicineRadiation therapyBlood–brain barrierGliomaDNA damagePharmacologyPathologyBiologyInternal medicineCentral nervous systemDNABiotechnologyGeneticsGlioma Diagnosis and TreatmentDNA Repair MechanismsMicrotubule and mitosis dynamics