Reduction-sensitive platinum (IV)-prodrug nano-sensitizer with an ultra-high drug loading for efficient chemo-radiotherapy of Pt-resistant cervical cancer in vivo
Kejun Luo, Wenxuan Guo, Yanting Yu, Simeng Xu, Min Zhou, Keqi Xiang, Kun Niu, Xianqi Zhu, Guangying Zhu, Zheng An, Qingsong Yu, Zhihua Gan
Topics & Concepts
CisplatinProdrugHeLaIn vivoChemistryGlutathionePharmacologyChemoradiotherapyApoptosisCancer cellCancer researchCancerIn vitroChemotherapyBiochemistryMedicineSurgeryInternal medicineBiologyEnzymeBiotechnologyNanoplatforms for cancer theranosticsMetal complexes synthesis and propertiesNanoparticle-Based Drug Delivery