Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia
Jan Deprest, K. H. Nicolaides, Alexandra Benachi, E. Gratacós, Greg Ryan, Nicola Persico, Haruhiko Sago, Anthony Johnson, Mirosław Wielgoś, Christoph Berg, Ben Van Calster, Francesca Maria Russo
Abstract
(Abstracted from N Engl J Med 2021;385:107–118) Congenital diaphragmatic hernia (CDH) occurs in approximately 1 in 4000 births, and 85% of these cases have the defect on the left side. The condition is associated with neonatal death due to respiratory failure and pulmonary hypertension.
Topics & Concepts
MedicineCongenital diaphragmatic herniaDiaphragmatic herniaDiaphragmatic breathingRandomized controlled trialSurgeryFetusRespiratory failureHerniaPregnancyGeneticsBiologyAlternative medicinePathologyCongenital Diaphragmatic Hernia StudiesHernia repair and management