A practical synthesis of amino limonin/deoxylimonin derivatives as effective mitigators against inflammation and nociception
Shaochi Wang, Xueqing Han, Yun Yang, Rui Chen, Zhaoyi Guo, Qihua Zhu, Yungen Xu
Abstract
, were selected for further investigation by a carrageenan-induced mouse paw edema model, both of which displayed a dose-response dependent manner and demonstrated superior anti inflammation capacity to that of indomethacin in the first 2 hours.
Topics & Concepts
LimoninNociceptionNeurosciencePsychologyChemistryChromatographyReceptorBiochemistryPhytochemical compounds biological activitiesTraditional and Medicinal Uses of AnnonaceaePhytochemistry and Bioactive Compounds