CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface TLR9 to enhance the antibody response to vaccine
Wenting Lu, Cuiyun Cui, Yangyang Wang, Xiaomeng Sun, Shengnan Wang, Ming Yang, Yongli Yu, Liying Wang
Topics & Concepts
CpG OligodeoxynucleotideTLR9AdjuvantCD80CD86CD40AntibodyBiologyCpG siteImmunologyB cellImmune systemMolecular biologyCell biologyT cellCytotoxic T cellGene expressionGeneIn vitroDNA methylationBiochemistryImmune Response and InflammationHepatitis B Virus StudiesImmunotherapy and Immune Responses