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Tumor-derived extracellular vesicles induce invalid cytokine release and exhaustion of CD19 CAR-T Cells

Xiaoying Zhu, Hui Hu, Yi Xiao, Qing Li, Zhaodong Zhong, Jingmin Yang, Ping Zou, Yang Cao, Fankai Meng, Wei Li, Yong You, An‐Yuan Guo, Xiaojian Zhu

2022Cancer Letters32 citationsDOI

Topics & Concepts

CD19Chimeric antigen receptorT cellCytokineImmunologyCD8Immune systemCell biologyCytotoxic T cellBiologyCancer researchChemistryIn vitroBiochemistryCAR-T cell therapy researchNanowire Synthesis and ApplicationsImmune Cell Function and Interaction
Tumor-derived extracellular vesicles induce invalid cytokine release and exhaustion of CD19 CAR-T Cells | Litcius