Substrate-controlled [4+1] and [3+2] annulations of ninhydrin-derived Morita–Baylis–Hillman carbonates to access polysubstituted furans and cyclopentenes
Kai‐Kai Wang, LI Yan-li, Yafei Li, Weiwei Yao, Lanxin Li, Xiao‐Long He, Rongxiang Chen
Abstract
classical [3+2] annulations by employing ninhydrin-derived MBH carbonates with 2-arylidene-1,3-indandiones under the same catalytic conditions. Furthermore, the structures of two kinds of cycloadducts were straightforwardly confirmed through X-ray diffraction analysis.
Topics & Concepts
NinhydrinAnnulationSubstrate (aquarium)ChemistryCatalysisOrganic chemistryMedicinal chemistryBiologyAmino acidEcologyBiochemistryAsymmetric Synthesis and CatalysisSynthetic Organic Chemistry MethodsCatalytic C–H Functionalization Methods