A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts
Bingjie Zhang, Simeng Zhao, Dehua Yang, Yiran Wu, Xin Ye, Haijie Cao, Xi‐Ping Huang, Xiaoqing Cai, Wen Sun, Na Ye, Yueming Xu, Yao Peng, Suwen Zhao, Zhi‐Jie Liu, Guisheng Zhong, Ming‐Wei Wang, Wenqing Shui
Abstract
[This corrects the article DOI: 10.1021/acscentsci.9b01125.].
Topics & Concepts
G protein-coupled receptorAporphineFunctional selectivityDrug discoveryReceptorAgonistComputational biologyChemistryDrugIn vivoPharmacologyBiologyBiochemistryStereochemistryAlkaloidBiotechnologyReceptor Mechanisms and SignalingComputational Drug Discovery MethodsNeuropeptides and Animal Physiology